AOD 9604: The Fat-Burning Peptide Designed for Targeted Body Recomposition
If diet and exercise alone aren't moving the needle on stubborn body fat — especially around the abdomen, hips, and thighs — AOD 9604 peptide therapy may be the targeted support your metabolism needs. At Prime Balance in Bradenton, FL, our physician-supervised protocols combine AOD 9604 with individualized treatment plans to help you lose fat, preserve lean muscle, and achieve lasting results.
WHAT IS AOD 9604?
AOD 9604 is a synthetic peptide derived from the C-terminal fragment of human growth hormone (HGH), specifically amino acids 177–191 of the HGH molecule. Originally developed in Australia as an anti-obesity treatment, it was designed to harness the fat-metabolizing properties of growth hormone — without the unwanted hormonal side effects that come with full HGH therapy.
Unlike traditional HGH, AOD 9604 does not stimulate IGF-1 production, does not affect blood sugar levels, and does not promote tissue or organ growth. Its action is highly selective: it targets adipose (fat) tissue and works to break down stored fat while inhibiting the formation of new fat cells.
How AOD 9604 Works
AOD 9604 works through two primary mechanisms that set it apart from other weight loss approaches:
1. Stimulates Lipolysis AOD 9604 activates the breakdown of stored fat cells — a process called lipolysis — by enhancing the sensitivity of beta-3 adrenergic receptors in fat tissue. These receptors are the main triggers for fat cell breakdown in the body. By upregulating their activity, AOD 9604 increases the rate at which stored fat is mobilized and burned for energy.
2. Inhibits New Fat Formation Beyond burning existing fat, AOD 9604 also helps prevent the formation of new fat cells (lipogenesis) by inhibiting key enzymes involved in fatty acid synthesis. Research suggests it may reduce lipogenic activity and decrease the conversion of carbohydrates into stored body fat — making it effective for both fat loss and long-term weight maintenance.
Importantly, AOD 9604 achieves this without raising IGF-1 levels, causing insulin resistance, or disrupting glucose metabolism — concerns commonly associated with full-length HGH therapy.
Benefits of AOD 9604 Peptide Therapy
Targeted reduction of stubborn body fat, particularly visceral and abdominal fat
Preserves lean muscle mass during fat loss
Does not affect blood sugar or insulin sensitivity
No IGF-1 stimulation — avoiding the growth-promoting effects of full HGH
Well-tolerated safety profile across clinical studies
Supports body recomposition when combined with diet and exercise
Results typically seen within 8–12 weeks of consistent treatment
Is AOD 9604 Right for You?
OD 9604 may be a strong fit if you:
Struggle with stubborn body fat that resists diet and exercise
Want to lose fat without compromising lean muscle
Are looking for a targeted approach that does not affect blood sugar or hormonal function
Have had limited results with GLP-1 medications like semaglutide or tirzepatide alone
Are interested in combining peptide therapy with a medically supervised weight loss program
At Prime Balance, AOD 9604 is often used alongside our other treatments — including Testosterone Replacement Therapy (TRT), Semaglutide, and Tirzepatide — for a comprehensive, individualized approach to body recomposition and metabolic health.
AOD 9604 vs. Semaglutide — What's the Difference?
| AOD 9604 | Semaglutide / Tirzepatide | |
|---|---|---|
| Mechanism | Directly targets fat cell metabolism | Suppresses appetite via GLP-1 receptors |
| Primary Effect | Fat breakdown and prevention of new fat formation | Reduced caloric intake |
| Blood Sugar Impact | None | Improves insulin sensitivity |
| Muscle Preservation | Yes | Variable |
| Best For | Stubborn fat, body recomposition | Significant weight loss, appetite control |
| Can Be Combined? | Yes | Yes |
Many patients at Prime Balance benefit from combining AOD 9604 with GLP-1 medications for a dual approach: appetite control through semaglutide or tirzepatide, and direct fat metabolism support through AOD 9604.
Ready to Lose Stubborn Fat with AOD 9604?
Schedule your free discovery call or in-person consultation at our Bradenton clinic. Our team will review your health history, discuss your goals, and determine if AOD 9604 peptide therapy is right for you.